ACT yeast self-reproduction

Answer
YES for the viable starter culture.
NO for accurate self-reproduction in the non-digital contrast lineage.

Reason Why
The starter genome is treated as a replicator storing digital hereditary information, while the cell machinery is treated as the vehicle that enables metabolism and copying support. Under no-design laws, digital information makes accurate genome copying possible. Because the replicator is accurate and paired with a vehicle, the whole starter cell qualifies as a self-reproducer. With a variation source and a selection environment, natural selection also becomes possible. By contrast, the non-digital lineage cannot support accurate genome copying under the same no-design-laws assumption, so it cannot sustain the same accurate self-reproduction or natural-selection story.

Check
C1  OK - no-design laws are assumed
C2  OK - digital information is physically instantiated for the viable lineage
C3  OK - a viable replicator is present
C4  OK - a viable vehicle is present
C5  OK - accurate genome copying is possible for the viable lineage
C6  OK - the viable lineage has a replicator-plus-vehicle architecture
C7  OK - the starter cell qualifies as a self-reproducer
C8  OK - heritable variation is possible for the viable lineage
C9  OK - the viable starter culture can support a natural-selection lineage
C10 OK - the fitter viable variant is selected in the fermenter
C11 OK - the non-digital contrast genome cannot be copied accurately under no-design laws
C12 OK - the non-digital contrast cell cannot achieve accurate self-reproduction
C13 OK - the non-digital contrast cell cannot support the same natural-selection lineage